AABA 2022 – Art, Orality, and Migration: The roles of NF1, mnemonics, and somatic adaptation in the hominin biocultural toolkit
I presented our research in a poster session at the in-person portion of the conference in Denver and also as a virtual podium presentation in the online portion of the conference. Both versions can be found below.
Poster
Will be on display as Poster #54 on Thursday, March 24th 8:00-6:30 in the “Genetics & Genomics: Evolution and Populations” #AABA2022 poster session in the Plaza Foyer, Sheraton Denver Downtown Hotel.
Presentation Video
Will be presented and discussed in the “Genetics & Genomics: Adaptation and Complex Traits” #AABA2022 online session on Tuesday, March 29th from 5:00-6:00 pm MDT.
References
- Altschul, S.F. et al. (1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
- Alveshere, A.J. & Riccardi, V.M. (2020). The Human NF1 Locus: A unique hominin genotype with potential evolutionary significance. Paper presented at the 89th annual conference of the American Association of Physical Anthropologists, Los Angeles, CA (virtual due to pandemic).
- Bloomfield, G. et al. (2015). Neurofibromin controls macropinocytosis and phagocytosis in Dictyostelium. eLife, 4, e04940.
- Cota B.C.L., et al. (2018). Amusia and its electrophysiological correlates in neurofibromatosis type 1. Arquivos de Neuro-Psiquiatria 76(5), 287-295
- Evrony et al. (2016). Resolving rates of mutation in the brain using single-neuron genomics. eLife, 5, e12966.
- Fisher S. E. (2019). Human Genetics: The Evolving Story of FOXP2. Current Biology: CB, 29(2), R65–R67.
- Fisher, S. E., & Scharff, C. (2009). FOXP2 as a molecular window into speech and language. Trends in Genetics 25(4), 166–177.
- Formicola, V. (2007). From the Sunghir Children to the Romito Dwarf: Aspects of the Upper Paleolithic Funerary Landscape. Current Anthropology, 48(3), 446–453.
- Hamacher, D. et al. (2022). The First Astronomers: How Indigenous Elders read the stars. Allen & Unwin
- Helfferich, J. et al. (2016) Neurofibromatosis type 1 associated low grade gliomas: A comparison with sporadic low grade gliomas, Critical Reviews in Oncology/Hematology 104:30-41
- Kelly, L. (2015). Knowledge and Power in Prehistoric Societies: Orality, Memory, and the Transmission of Culture. Cambridge
- Kelly, L (2020). Memory Craft. Pegasus
- Levine TM, et al. (2006). Cognitive profile of neurofibromatosis type 1. Semin Pediatr Neurol 13:8-20
- Lodato, M. A., et al. (2015). Somatic mutation in single human neurons tracks developmental and transcriptional history. Science (New York, N.Y.), 350(6256), 94–98.
- Masgras, I. et al. (2007). Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1, Cell Reports 18(3): 659-672
- Melloni, G., et al. 2019. Risk of Optic Pathway Glioma in Neurofibromatosis Type 1: No Evidence of Genotype–Phenotype Correlations in a Large Independent CohortCancers 11(12), 1838
- Meyer M. et al. (2012). A High-Coverage Genome Sequence from an Archaic Denisovan Individual. Science 201; 338(6104):222-6
- Morley, I. (2006). Hunter-gatherer music and its implications for identifying intentionality in the use of acoustic space. In C. Scarre & G. Lawson (Eds.), Archaeoacoustics (pp. 95-105). Cambridge: McDonald Institute for Archaeological Research.
- Nunn, P. (2018). The Edge of Memory: Ancient Stories, Oral Tradition and the Post-Glacial World. Bloomsbury
- Neale, M. & Kelly, L (2020). Songlines (First Knowledges): The Power and Promise. Thames & Hudson Australia
- Petru, Simona. (2019). Identity and Fear – Burials in the Upper Palaeolithic. Documenta Praehistorica. 45. 6-13. 10.4312/dp.45-1.
- Silva, A.,et al. (1997). A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nat Genet 15, 281–284 https://doi.org/10.1038/ng0397-281
- Staes, N. et al. (2017). FOXP2 variation in great ape populations offers insight into the evolution of communication skills. Scientific reports, 7(1), 16866. https://doi.org/10.1038/s41598-017-16844-x
- Upadhyaya, M., Cooper, M.N. , Ed.s (2012). Neurofibromatosis Type 1: Molecular and Cellular Biology. Springer
- Watkins, K. E. et al. (2002). Behavioural analysis of an inherited speech and language disorder: comparison with acquired aphasia. Brain: a journal of neurology, 125(Pt 3), 452–464.
Image Credits
- Blue Marble: Next Generation+topography+bathymetry. Equirectangular projection. Reto Stöckli, NASA Earth Observatory, modified by NordNordWest, Public domain, via Wikimedia Commons. https://commons.wikimedia.org/wiki/File:Blue_Marble_Next_Generation_%2B_topography_%2B_bathymetry.jpg
- Upper Paleolithic rock art panel. Leang Tedongnge Cave, Sulawesi, Indonesia. Oktaviana, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons. Cropped. https://commons.wikimedia.org/wiki/File:Leang_Tedongnge_rock_art_panel_credit_AA_Oktaviana-01.jpg
- Upper Paleolithic bone flute. Divje Babe, Slovenia. dalbera from Paris, France, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons. Cropped https://commons.wikimedia.org/wiki/File:Fl%C3%BBte_pal%C3%A9olithique_(mus%C3%A9e_national_de_Slov%C3%A9nie,_Ljubljana)_(9420310527).jpg
- Upper Paleolithic bone flute, Geissenklösterle. José-Manuel Benito Álvarez, CC BY-SA 2.5 <https://creativecommons.org/licenses/by-sa/2.5>, via Wikimedia Commons. Cropped. https://commons.wikimedia.org/wiki/File:Flauta_paleol%C3%ADtica_blanco.jpg
- Serranía de la Lindosa Rock Paintings, northwestern Colombia; Las Dantas panel at Cerro Azul, La Lindosa (arrow points to proposed giant sloth painting). Iriarte et al., CC BY 4.0 <https://creativecommons.org/licenses/by/4.0>, via Wikimedia Commons https://commons.wikimedia.org/wiki/File:Serrania_de_la_Lindosa_rock_paintings_-_Iriarte_et_al_2022.jpg
- Hopi Pueblo. Kachina doll (Sa’lakwmana), late 19th century. Wood, pigment, 9 x 7 1/2 x 3 1/2 in. (22.9 x 19.1 x 8.9 cm). Brooklyn Museum, Museum Expedition 1904, Museum Collection Fund, 04.297.5543. Creative Commons-BY (Photo: Brooklyn Museum, 04.297.5543_transp6238.jpg) https://www.brooklynmuseum.org/opencollection/objects/17012
- The Blue Marble. NASA Apollo 17, Public domain, via Wikimedia Commons. https://commons.wikimedia.org/wiki/File:The_Blue_Marble.jpg
- Chimpanzee, human reflection. Stephanie Clifford from Arlington, VA, USA, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons. https://commons.wikimedia.org/wiki/File:Chimpanzee_(4407365183).jpg
- One dead and many newborn hippocampal neurons. Confocal microscopy AlmudenaFM, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons. https://upload.wikimedia.org/wikipedia/commons/0/06/Death_eyes.jpg
- Artist’s impression of Upper Paleolithic double burial. Sunghir, Russia. Libor Balák, Anthropark http://www.anthropark.wz.cz/gravetta.htm
- Dictyostelium discoideum fruiting bodies and slug. Usman Bashir, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons https://commons.wikimedia.org/wiki/File:Dictyostelium_discoideum_02.jpg